ea0035p513 | Endocrine disruptors | ECE2014
Hansen Juliana Frohnert
, Brorson Marianne Moller
, Hartoft-Nielsen Marie-Louise
, Boas Malene
, Main Katharina M
, Frederiksen Hanne
, Hofman-Bang Jacob
, Rasmussen AEse Krogh
, Feldt-Rasmussen Ulla
Introduction: Phthalates are suspected to influence thyroid function in epidemiologic and experimental animal studies. The aim of the study was to investigate the ability of primary human thyroid cell cultures to metabolise phthalates and a possible concentration-dependent response of phthalates on thyroglobulin (Tg) secretion.Methods: Human thyrocytes obtained from thyroidectomies were cultured to confluent monolayers. These were exposed to DEHP in conc...